Tactile-like corpuscles in gastric mucosa: a case report
2006

Tactile-like corpuscles in gastric mucosa: a case report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Salim Sadia, Liu Beiqing, Mahmoodi Mandana, Asad Haider, Hou Steve J

Primary Institution: Drexel University College of Medicine

Conclusion

This case is the first report of tactile corpuscle-like structures in gastric mucosa, which were previously only documented in benign colonic mucosa.

Supporting Evidence

  • The presence of tactile corpuscle-like structures in Schwannomas and Neurofibromas is well-documented.
  • Histopathology revealed poorly differentiated adenocarcinoma in the patient.
  • Immunohistochemical staining showed strong positivity for S-100, indicating a neurogenic origin.

Takeaway

Doctors found tiny structures in the stomach that look like nerve endings, which is unusual because they usually only see them in tumors.

Methodology

The case involved examining tissue samples from a patient who underwent esophagogastrectomy, using hematoxylin and eosin staining and immunohistochemical methods.

Limitations

The study is based on a single case, limiting the generalizability of the findings.

Participant Demographics

30-year-old Caucasian male with a history of smoking and heavy alcohol use.

Digital Object Identifier (DOI)

10.1186/1477-7819-4-39

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