A simple method for characterizing left ventricular remodeling by cardiovascular magnetic resonance
2011
Characterizing Left Ventricular Remodeling with Cardiac MRI
Sample size: 137
publication
Evidence: moderate
Author Information
Author(s): Pun Shawn C, Figura Maria, Chow Kelvin, Haykowsky Mark, Thompson Richard, Paterson Ian
Primary Institution: University of British Columbia
Hypothesis
The LVRI would accurately reflect underlying pathophysiology.
Conclusion
The LVRI is a simple method for quantifying left ventricular remodeling in various cardiac conditions.
Supporting Evidence
- The mean LVRI for controls was 0.87±0.1g/ml.
- Mean LVRI was elevated in inflammatory and pressure loaded groups compared to controls.
- Mean LVRI was reduced in ischemic and volume loaded groups compared to controls.
- There was no statistically significant difference in LVRI between males and females.
Takeaway
This study found a way to measure how the heart changes shape in different heart conditions using a special type of imaging.
Methodology
Quantitative volumetric analyses were performed using standard imaging analysis software on 105 cases and 32 healthy controls.
Participant Demographics
89 males, mean age 48±18; 32 healthy volunteers as controls.
Statistical Information
P-Value
p=0.002, p=0.014, p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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