Prognostic Factors in Colon Cancer
Author Information
Author(s): Grande Michele, Milito Giovanni, Attinà Grazia Maria, Cadeddu Federica, Muzi Marco Gallinella, Nigro Casimiro, Rulli Francesco, Farinon Attilio Maria
Primary Institution: University Hospital Tor Vergata
Hypothesis
What clinical, laboratory, and morphological factors influence the prognosis of colon cancer?
Conclusion
Different clinical, laboratory, and patho-morphological parameters have varying prognostic values for colon carcinoma.
Supporting Evidence
- Depth of tumor invasion, type of operation, and CT scanning were significant predictors of survival.
- Fibrinogen value was the most statistically significant variable related to tumor invasion.
- The study suggests that preoperative prognostic markers will gain relevance for treatment decisions.
Takeaway
Doctors looked at many factors to see how they affect survival in colon cancer patients. They found some important signs that can help predict how well patients will do.
Methodology
Retrospective analysis of 92 patients with colon cancer who underwent surgical resection, analyzing various clinical, laboratory, and patho-morphological parameters.
Limitations
The study is limited by its retrospective nature and the small sample size.
Participant Demographics
48 males and 44 females, aged 37 to 94 years, average age 69.2 years.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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