Effectiveness of a Chinese herbal medicine preparation in the treatment of cough in uncomplicated upper respiratory tract infection: a randomised double-blinded placebo-control trial
2006

Effectiveness of Chinese Herbal Medicine for Cough in Upper Respiratory Infections

Sample size: 82 publication Evidence: moderate

Author Information

Author(s): WCW Wong, A Lee, AT Lam, KT Li, CYM Leung, PC Leung, ELY Wong, JL Tang

Primary Institution: The Chinese University of Hong Kong

Hypothesis

Is a Chinese herbal medicine preparation effective in treating cough caused by uncomplicated upper respiratory tract infections?

Conclusion

The Chinese herbal medicine preparation was well-tolerated and showed some benefits in treating cough, but did not significantly outperform placebo overall.

Supporting Evidence

  • 62 patients completed the trial with no adverse effects reported.
  • Both treatment and control groups showed improvement in cough scores.
  • Women taking TCM had fewer problems with sputum production.
  • Older subjects reported significant improvement in hoarseness.

Takeaway

This study looked at a herbal medicine for cough and found it was safe to use, but it didn't work better than a sugar pill.

Methodology

A randomised, double-blinded, placebo-controlled trial was conducted with 82 patients over 5 days.

Potential Biases

Potential bias due to the expectation of immediate relief from participants accustomed to Western treatments.

Limitations

The study had a high dropout rate and relied on self-reported measures, which may introduce bias.

Participant Demographics

Participants were mainly young working adults from Hong Kong, with a majority being female.

Statistical Information

P-Value

p = 0.03 for sputum production in women; p = 0.05 for hoarseness in older subjects.

Digital Object Identifier (DOI)

10.1186/1745-9974-2-5

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