Phytochemical Study and In Vitro Antioxidant Activity of Helianthemum cinereum Along with Antitumor Activity of the Isolated trans-Tiliroside and Luteolin 4′-O-β-Xyloside
2024

Study of Helianthemum cinereum's Antioxidant and Antitumor Properties

publication 10 minutes Evidence: moderate

Author Information

Author(s): Bertella Anis, Smadi Abla, Benhabrou Hakim, Salvador Diana, Wrona Magdalena, Oliveira Helena, Sidaoui Abouamama, Gavril-Luminita Georgiana, Pinto Diana C. G. A., Olewnik-Kruszkowska Ewa, Nerín Cristina, Silva Artur M. S., Bitam Fatma, Ferrante Claudio

Primary Institution: Department of Molecular and Cellular Biology, Faculty of Life and Nature Sciences, Abbes Laghrour University Khenchela, Algeria

Hypothesis

The extracts of Helianthemum cinereum will exhibit significant antioxidant and antitumor activities.

Conclusion

Helianthemum cinereum extracts show strong antioxidant capacity and potential antitumor effects against various cancer cell lines.

Supporting Evidence

  • Twelve compounds were isolated and identified from Helianthemum cinereum.
  • The ethyl acetate extract showed a high amount of phenolic and flavonoid compounds.
  • Antioxidant activity was determined using DPPH, FRAP, and ABTS methods.
  • Trans-tiliroside and luteolin 4′-O-β-xyloside were evaluated for their antitumor activity against several cancer cell lines.
  • The study highlights the potential of Helianthemum cinereum as a source of natural antioxidants.

Takeaway

This study found that a plant called Helianthemum cinereum can help fight cancer and has strong abilities to protect against damage from bad things in our bodies.

Methodology

The study involved isolating compounds from Helianthemum cinereum extracts and testing their antioxidant and antitumor activities using various assays.

Limitations

The study did not explore the long-term effects of the extracts or their efficacy in vivo.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/molecules29245935

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