Therapeutic Potential of Nutritional Aryl Hydrocarbon Receptor Ligands in Gut-Related Inflammation and Diseases
2024

Therapeutic Potential of Nutritional Aryl Hydrocarbon Receptor Ligands in Gut-Related Inflammation and Diseases

publication Evidence: moderate

Author Information

Author(s): Huang Fu-Chen

Primary Institution: Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan

Hypothesis

Nutritional Aryl Hydrocarbon Receptor (AhR) ligands can modulate intestinal immunity and have therapeutic potential for gut-related diseases.

Conclusion

Nutritional AhR ligands may serve as promising therapeutic strategies for managing gut-related inflammation and diseases.

Supporting Evidence

  • Nutritional AhR ligands can enhance immune responses and maintain gut health.
  • These ligands may help in treating conditions like inflammatory bowel disease and colorectal cancer.
  • Research indicates that dietary sources of AhR ligands can modulate gut microbiota.
  • Activation of AhR by these ligands can improve intestinal barrier function.
  • AhR signaling is crucial for the regulation of immune responses in the gut.

Takeaway

Certain foods can help our body's defenses in the gut, which can make us healthier and prevent diseases.

Digital Object Identifier (DOI)

10.3390/biomedicines12122912

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