Efficacy of Hovenia dulcis Fruit Extract in Hangover Mitigation: Double-Blind Randomized Clinical Evaluation
2024

Hovenia dulcis Fruit Extract Helps Reduce Hangover Symptoms

Sample size: 30 publication 10 minutes Evidence: moderate

Author Information

Author(s): Paik Dong Hyun, Lee Ki Won, Shim Youn Young, Reaney Martin J. T., Park Ilbum, Lee Sang-Hun, Park Jong-Yul, Park Euddeum, Lee Sung-Bum, Kim In Ah, Xu Guangpeng, Hong Ji Youn, Kim Young Jun, Yang Runqiang, Yin Yongqi

Primary Institution: Global Medical Research Center, Seoul, Republic of Korea

Hypothesis

Does Hovenia dulcis fruit extract effectively mitigate hangover symptoms?

Conclusion

The study found that Hovenia dulcis extract can significantly lower blood alcohol and acetaldehyde levels, suggesting its potential as a remedy for hangover symptoms.

Supporting Evidence

  • The blood alcohol concentrations of the HDB and HDPB groups were significantly lower compared to the PLA group at 0.5 and 6 hours post-consumption.
  • The blood acetaldehyde concentrations in the HDPB group were significantly lower than the PLA group after 6 hours.
  • Participants reported reduced hangover symptoms after consuming Hovenia dulcis extract.

Takeaway

This study shows that a fruit extract from Hovenia dulcis can help people feel better after drinking alcohol by lowering the amount of alcohol and a harmful substance called acetaldehyde in their blood.

Methodology

A randomized, double-blind, crossover, placebo-controlled clinical trial was conducted with 30 participants who consumed different beverages containing Hovenia dulcis extract and a placebo.

Potential Biases

Potential bias due to the involvement of authors affiliated with a pharmaceutical company.

Limitations

The study had a small sample size and was limited to participants aged 19 to 40 who had previously experienced hangovers.

Participant Demographics

12 males and 12 females, aged between 19 and 40 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/foods13244084

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