Novel Cellulose-Binding-Domain Protein in Phytophthora Is Cell Wall Localized
2011

Cellulose-Binding Protein in Phytophthora

publication Evidence: moderate

Author Information

Author(s): Richard W. Jones, Manuel Ospina-Giraldo

Primary Institution: United States Department of Agriculture-Agricultural Research Service

Hypothesis

Does Phytophthora infestans contain cellulose-binding domains associated with its cell wall proteins?

Conclusion

The study found that Phytophthora infestans has unique cellulose-binding proteins that are not associated with catalytic domains and do not elicit a plant hypersensitive response.

Supporting Evidence

  • Only five genes encoding cellulose-binding domains were found in Phytophthora infestans.
  • None of the identified proteins were associated with catalytic domains.
  • Immunolocalization showed that one of the proteins, CBD1, is embedded in the hyphal cell wall.

Takeaway

The researchers looked for proteins in a plant pathogen that help it attach to plant cells, but they found that these proteins don't trigger a plant's defense system.

Methodology

A genome-wide survey for carbohydrate binding module family 1 (CBM1) was performed, followed by immunolocalization and expression tests in plants.

Limitations

The study did not identify any elicitor activity from the cellulose-binding protein CBD1, which was contrary to initial expectations.

Digital Object Identifier (DOI)

10.1371/journal.pone.0023555

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