Indicators of prognosis after hepatic resection for colorectal secondaries
1992

Liver Resection for Colorectal Secondaries

Sample size: 266 publication Evidence: moderate

Author Information

Author(s): J. Scheele, R. Stangl, A. Altendorf-Hofmann, F.P. Gall

Primary Institution: Medical School Observatory

Hypothesis

What factors influence prognosis after hepatic resection for colorectal cancer metastases?

Conclusion

Surgical resection of liver metastases can lead to long-term disease-free survival in selected patients, even with extrahepatic disease.

Supporting Evidence

  • Patients with positive margins of resection had poorer survival outcomes.
  • Presence of satellite metastases significantly decreased survival rates.
  • Long-term survival was observed in patients with complete resection of liver metastases.

Takeaway

Doctors can sometimes remove liver tumors from people with colon cancer, and some of those people can live a long time without getting sick again.

Methodology

Patients who underwent liver resection for colorectal cancer were followed for survival outcomes and analyzed for various prognostic factors.

Potential Biases

Potential selection bias in patient eligibility for surgery.

Limitations

The study may not generalize to all patients with colorectal cancer due to its single-institution nature.

Participant Demographics

Patients with colorectal cancer metastases to the liver, treated between 1960 and 1988.

Statistical Information

P-Value

0.0003

Statistical Significance

p<0.05

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