ASSOCIATION OF PRO-INFLAMMATORY DIET WITH FRAILTY ONSET AMONG ADULTS WITH AND WITHOUT DEPRESSIVE SYMPTOMS
2024

Pro-Inflammatory Diet and Frailty Onset

Sample size: 1701 publication Evidence: moderate

Author Information

Author(s): Millar Courtney, Dufour Alyssa, Hebert James, Shivappa Nitin, Okereke Olivia, Kiel Douglas, Hannan Marian, Sahni Shivani

Primary Institution: Hebrew SeniorLife

Hypothesis

The study aims to determine the association between a pro-inflammatory diet and frailty onset in individuals with and without depressive symptoms.

Conclusion

A pro-inflammatory diet is linked to a higher risk of frailty, especially in individuals with depressive symptoms.

Supporting Evidence

  • The study included 1,701 non-frail individuals with dietary and depressive symptom data.
  • Higher E-DII scores indicate a more pro-inflammatory diet.
  • Increased odds of frailty were observed with higher E-DII scores, particularly in those with depressive symptoms.

Takeaway

Eating foods that cause inflammation can make people weaker, especially if they are feeling sad.

Methodology

This prospective study evaluated dietary inflammatory index and depressive symptoms in non-frail individuals over a follow-up period.

Limitations

The study is preliminary and requires further investigation.

Participant Demographics

Mean age was 58 years, with 45% male participants.

Statistical Information

Confidence Interval

95% CI: 1.05-1.24 for those without depressive symptoms; 95% CI: 1.13-2.13 for those with depressive symptoms.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0654

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