Reply: TIMP-1 enhancer sequence – real or bacterial?
2003
Discussion on TIMP-1 Gene Characterization
Editorial
Author Information
Author(s): Stearns M E, Hu Y, Wang M
Primary Institution: Drexel University College of Medicine
Conclusion
The TIMP-1 gene shows high homology with both human and bacterial sequences.
Supporting Evidence
- The TIMP-1 gene was cloned from PC-3 ML genomic DNA.
- Sequencing revealed 97% homology with the human TIMP-1 promoter region.
- Blast analysis showed 96% homology with the coding region of E. coli TIMP-1.
Takeaway
Scientists studied a gene called TIMP-1 and found it is very similar to genes in humans and bacteria.
Methodology
The TIMP-1 gene was sequenced and analyzed for homology with other sequences.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website