Lifetime exercise activity and breast cancer risk among post-menopausal women
1999

Exercise and Breast Cancer Risk in Post-Menopausal Women

Sample size: 2027 publication Evidence: moderate

Author Information

Author(s): Carpenter C L, Ross R K, Paganini-Hill A, Bernstein L

Primary Institution: University of Southern California School of Medicine

Hypothesis

Is lifetime exercise activity related to breast cancer risk among post-menopausal women?

Conclusion

Strenuous exercise appears to reduce breast cancer risk among post-menopausal women who do not gain sizable amounts of weight during adulthood.

Supporting Evidence

  • Women who exercised at least 17.6 MET-hours since menarche had a lower breast cancer risk.
  • Exercise was not protective for women who gained considerable weight during adulthood.
  • Breast cancer risk was reduced for women who consistently exercised at high levels throughout their lifetime.
  • Women who exercised more than 4 hours per week for at least 12 years had a lower risk.
  • Vigorous exercise during the most recent 10 years was associated with reduced risk.

Takeaway

If post-menopausal women exercise regularly, they may lower their chances of getting breast cancer, especially if they maintain a stable weight.

Methodology

Population-based case-control study of post-menopausal white women aged 55–64.

Limitations

The study did not evaluate the impact of exercise on women who gained considerable weight during adulthood.

Participant Demographics

Post-menopausal white women aged 55–64 living in Los Angeles County, California.

Statistical Information

Confidence Interval

95% CI 0.37–0.83; 95% CI 0.24–0.75; 95% CI 0.40–0.88; 95% CI 0.32–0.85

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690610

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