Inhibition of IL-1b and TNF-a Secretion from Resting and Activated Human Immunocytes by the Homeopathic Medication Traumeel
2004

Effects of Traumeel on Immune Cell Inflammation

publication Evidence: moderate

Author Information

Author(s): Svetlana Porozov, Liora Cahalon, Michael Weiser, David Branski, Ofer Lider, Menachem Oberbaum

Primary Institution: The Center for Integrative Complementary Medicine, Shaare Zedek Medical Center

Hypothesis

Does Traumeel inhibit the secretion of pro-inflammatory cytokines from human immune cells?

Conclusion

Traumeel significantly inhibits the secretion of pro-inflammatory cytokines IL-1b, TNF-a, and IL-8 from both resting and activated immune cells.

Supporting Evidence

  • Traumeel inhibited IL-1b secretion by up to 70% in both resting and activated cells.
  • TNF-a secretion was reduced by up to 65% in activated cells.
  • IL-8 secretion was reduced by 50% in both resting and activated cells.

Takeaway

Traumeel is a homeopathic medicine that helps reduce inflammation by stopping certain chemicals in the body that cause swelling.

Methodology

In vitro study measuring cytokine secretion from human T cells, monocytes, and gut epithelial cells after treatment with Traumeel.

Limitations

Further studies are needed to clarify the mode of action and confirm the clinical relevance of the findings.

Participant Demographics

Healthy human donors for T cells; specific demographics not provided.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1080/10446670410001722203

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