Clinicopathologic study associated with long-term survival in Japanese patients with node-negative breast cancer
2000

Long-term survival in Japanese patients with node-negative breast cancer

Sample size: 200 publication Evidence: moderate

Author Information

Author(s): Kato T, Kimura T, Miyakawa R, Fujii A, Yamamoto K, Kameoka S, Nishikawa T, Kasajima T

Primary Institution: Tokyo Women's Medical University

Hypothesis

This study aims to determine the value of blood vessel invasion and other factors in predicting survival rates in patients with node-negative breast cancer.

Conclusion

Blood vessel invasion, PCNA, and tumor size are important indicators for long-term survival in Japanese patients with node-negative breast cancer.

Supporting Evidence

  • BVI, PCNA, and tumor size were found to be independent prognostic factors.
  • The study followed patients for a median of 10 years.
  • 10.5% of patients had recurrence and 7.5% died of breast cancer.

Takeaway

The study found that certain factors can help doctors predict how long patients with a specific type of breast cancer might live.

Methodology

The study analyzed various clinicopathological factors in 200 patients with node-negative breast cancer over a median follow-up of 10 years.

Participant Demographics

Japanese patients with node-negative breast cancer.

Statistical Information

P-Value

P = 0.0159, P = 0.0368, P = 0.0165, P = 0.0001, P = 0.0190, P = 0.0399

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1054/bjoc.1999.0934

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