Preparation of Green Tea Polyphenol-Loaded Diacylglycerol Nanostructured Lipid Carrier Hydrogels and Their Activities Related to Skin Protection
2024

Green Tea Polyphenol-Loaded Diacylglycerol Hydrogels for Skin Protection

publication Evidence: high

Author Information

Author(s): Zhu Zhini, Xia Qiu, Zhan Xinxia, Li Wenyuan, He Xuan, Wang Bo, Zhou Qizhi, Huang Jian, Ye Yong, Koo Hyung-Jun

Primary Institution: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China

Hypothesis

Can a novel diacylglycerol nanostructured lipid carrier hydrogel improve the stability and skin application of green tea polyphenols?

Conclusion

The GTP-DAG-NLC-GEL shows significant potential for skin protection in cosmetics due to its high encapsulation rate and stability.

Supporting Evidence

  • The encapsulation rate and drug loading of GTP in GTP-DAG-NLC-GEL reached 86.7% and 2.6%, respectively.
  • The DPPH free radicals scavenging rate and inhibition rate of advanced glycation end-products were 85.46% and 89.72%, respectively.
  • The viscosity of GTP-DAG-NLC-GEL was 980 Pa·s at a shear rate of 5 rpm.

Takeaway

This study created a special gel that helps protect skin using green tea ingredients, making it better for cosmetics.

Methodology

The study involved preparing a diacylglycerol nanostructured lipid carrier hydrogel loaded with green tea polyphenols and evaluating its physical properties and skin protective effects.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/ma17246227

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