Risk factors for squamous cell carcinoma of the oesophagus in women: a case–control study
2001

Risk Factors for Oesophageal Cancer in Women

Sample size: 159 publication Evidence: moderate

Author Information

Author(s): Sharp L, Chilvers C E D, Cheng K K, McKinney P A, Logan R F A, Cook-Mozaffari P, Ahmed A, Day N E

Primary Institution: Department of Medicine & Therapeutics, University of Aberdeen

Hypothesis

What are the risk factors for squamous cell carcinoma of the oesophagus in women?

Conclusion

Eating salads and having a light breakfast may protect against oesophageal cancer, while drinking tea and smoking are risk factors.

Supporting Evidence

  • Eating salads was associated with a lower risk of oesophageal cancer.
  • Having a light breakfast was also linked to reduced cancer risk.
  • Drinking tea was identified as a risk factor for oesophageal cancer.
  • There was a significant trend with the temperature of hot drinks consumed.
  • Alcohol consumption did not show a relationship with cancer risk.
  • Years of smoking showed a significant trend with cancer risk.
  • Aspirin consumption had a protective effect in English centres.

Takeaway

This study found that some foods can help protect against a type of throat cancer, while other habits like drinking hot tea and smoking can increase the risk.

Methodology

A population-based matched case–control study with interviews about lifestyle and medical history.

Participant Demographics

Women in four regions of England and Scotland.

Statistical Information

P-Value

P = 0.03

Confidence Interval

95% CI 0.20–0.92

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1054/bjoc.2001.2147

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