Temporal and spatial trends in gastric cancer burden in the USA from 1990 to 2021: findings from the global burden of disease study 2021
2024

Trends in Gastric Cancer Burden in the USA (1990-2021)

publication 10 minutes Evidence: moderate

Author Information

Author(s): Zhan Chengwei, Qiu Binxu, Wang Jun, Li Yanhua, Yu Jinhai

Primary Institution: The First Hospital of Jilin University

Hypothesis

What are the temporal trends of gastric cancer burden in the USA from 1990 to 2021?

Conclusion

Gastric cancer remains a significant public health issue in the USA, with decreasing age-standardized rates but high absolute numbers of cases.

Supporting Evidence

  • From 1990 to 2021, the incidence and prevalence of gastric cancer in the USA increased.
  • Age-standardized incidence rates trended downward.
  • The burden of gastric cancer was significantly higher in males compared to females.
  • The highest incidence in females was in the 75-79 age group, while in males it was in the 70-74 age group.
  • Preventive interventions are crucial for men and patients over the age of 60.

Takeaway

Gastric cancer is a big problem in the USA, but while fewer people are getting it compared to before, many still have it, especially older men.

Methodology

The study used data from the Global Burden of Disease study, employing descriptive statistics, age-period-cohort analysis, and ARIMA modeling.

Potential Biases

Potential detection bias due to varying healthcare access across regions.

Limitations

The study relies on secondary data, which may have quality and reliability issues, and focuses on a limited number of risk factors.

Participant Demographics

The burden of gastric cancer is higher in males and individuals aged 60 and above.

Statistical Information

Confidence Interval

95% CI: -0.77 to -0.68

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fonc.2024.1499384

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