Precocious puberty in an infant with hepatoblastoma: a case report
2011
Precocious Puberty in an Infant with Hepatoblastoma
Sample size: 1
publication
Evidence: moderate
Author Information
Author(s): Al-Jumaily Usama, Sammour Ibrahim, Al-Muhaisen Fadi, Ajlouni Fatenah, Sultan Iyad
Primary Institution: King Hussein Cancer Center
Conclusion
The development of new chemotherapeutic agents and complete surgical resection are promising for treating virilizing hepatoblastoma.
Supporting Evidence
- The patient had elevated levels of alpha-fetoprotein and free testosterone.
- After treatment, the child's hormone levels returned to normal.
- No evidence of tumor recurrence was found 18 months after therapy.
Takeaway
A baby had early puberty because of a liver tumor, but after treatment, he got better and showed no signs of the tumor returning.
Methodology
The patient was treated with chemotherapy and surgery, with follow-up evaluations conducted.
Limitations
The case is based on a single patient, limiting generalizability.
Participant Demographics
15-month-old Asian male infant.
Digital Object Identifier (DOI)
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