Study of Shigella sonnei in Southern Italy
Author Information
Author(s): Mammina Caterina, Aleo Aurora, Romani Cristina, Nastasi Antonino
Primary Institution: Centre for Enteric Pathogens of southern Italy (CEPIM), University of Palermo
Hypothesis
What is the emergence timeline and genetic diversity of Shigella sonnei biotype g carrying class 2 integrons in southern Italy?
Conclusion
The study suggests that the emergence of biotype g class 2 integron carrying S. sonnei in southern Italy dates back to at least the late 1980s.
Supporting Evidence
- The study found that the earliest isolates from 1971-1980 were heterogeneous and lacked class 2 integrons.
- In contrast, isolates from 1981-2000 showed a consistent presence of class 2 integrons and related pulsotypes.
- The findings indicate a significant increase in the prevalence of multiresistant strains in the later decades.
Takeaway
This study looked at a type of bacteria that can make people sick and found that a specific strain has been around for a long time and is getting stronger.
Methodology
The study analyzed 31 clinical isolates of S. sonnei biotype g using biochemical tests, antimicrobial susceptibility testing, and pulsed field gel electrophoresis.
Limitations
The study is limited by the retrospective nature and the poor sensitivity of passive surveillance systems.
Participant Demographics
Clinical isolates from southern Italy identified between 1971 and 2000.
Digital Object Identifier (DOI)
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