Epileptic Seizures As the Sole Presentation of a Radiologically Isolated Syndrome: A Case Report and Review of the Literature
2024

Epileptic Seizures in Radiologically Isolated Syndrome: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Hazim Asmaa, Mimouni Yasmine, Hakimi Meriem, Saaf Sarra, El Azhari Meryem, El Yakoubi Zineb, Lhassani Sara, Kazzoul Loubna, Aasfara Jehanne, Ouhabi Hamid

Primary Institution: Mohamed VI University of Health Sciences, Casablanca, MAR

Hypothesis

Can seizures be the first presentation of radiologically isolated syndrome (RIS) in multiple sclerosis (MS)?

Conclusion

This case suggests that seizures may present early in the disease course of RIS, even without overt clinical symptoms of MS.

Supporting Evidence

  • Seizures are rarely described as the first presentation of MS.
  • The presence of radiological lesions suggests a potential risk for progression to clinically definite MS.
  • The relationship between RIS and epilepsy remains poorly understood.

Takeaway

A woman had a seizure that led to the discovery of brain lesions, showing that seizures can happen early in multiple sclerosis, even if there are no other symptoms.

Methodology

Case report and literature review.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

29-year-old female with no significant medical history.

Digital Object Identifier (DOI)

10.7759/cureus.75226

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