Risk of cervical cancer is not increased in Chinese carrying homozygous arginine at codon 72 of p53
1999
Cervical cancer risk and p53 gene variant in Chinese
publication
Author Information
Author(s): Ngan H Y S, Liu V W S, Liu S S
Primary Institution: University of Hong Kong
Hypothesis
Is there a correlation between homozygous arginine at codon 72 of p53 and the risk of cervical cancer in Chinese individuals?
Conclusion
The study found no correlation between the p53 gene variant and the risk of cervical cancer in Chinese individuals.
Supporting Evidence
- Homozygous arginine at codon 72 of p53 was found in 22% of normal cervices.
- 30.0% of cervical cancers had the homozygous arginine variant.
- No significant difference was detected between normal and cervical cancer cases regarding the p53 variant.
Takeaway
This study looked at a specific gene variant and found that it doesn't increase the risk of cervical cancer in Chinese people.
Participant Demographics
The study involved Chinese individuals.
Digital Object Identifier (DOI)
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