CoGemiR: A Comparative Genomics MicroRNA Database
Author Information
Author(s): Maselli Vincenza, Di Bernardo Diego, Banfi Sandro
Primary Institution: TIGEM Telethon Institute of Genetics and Medicine
Hypothesis
Can a new microRNA database provide a comparative overview of microRNA genomic organization and conservation across different species?
Conclusion
CoGemiR offers a user-friendly interface to explore the genomic organization of microRNAs and their conservation across evolution.
Supporting Evidence
- CoGemiR contains 5064 records of microRNAs across 36 species.
- The database includes both known and newly predicted microRNAs.
- CoGemiR allows users to see the same microRNA's genomic context in different species.
Takeaway
CoGemiR is a database that helps scientists see how microRNAs are organized in different species, making it easier to study their roles in gene regulation.
Methodology
The database was constructed using data from existing databases and new predictions, with a web interface for user queries.
Limitations
The database may not include all microRNAs from every species, and some data is limited to human and mouse.
Digital Object Identifier (DOI)
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