Oxidative stress
2011

Oxidative Stress in Pregnancy

publication Evidence: moderate

Author Information

Author(s): Burton Graham J., Jauniaux Eric

Primary Institution: Centre for Trophoblast Research, University of Cambridge

Hypothesis

Oxidative stress plays a central role in the pathophysiology of many complications of human pregnancy.

Conclusion

Oxidative stress is implicated in various pregnancy complications, including miscarriage and pre-eclampsia.

Supporting Evidence

  • Oxidative stress is linked to complications such as miscarriage and pre-eclampsia.
  • Reactive oxygen species can cause damage to cells and tissues during pregnancy.
  • Antioxidant defenses are crucial for maintaining balance against oxidative stress.

Takeaway

Oxidative stress is like a bad guy that can hurt the baby during pregnancy, causing problems like miscarriage and other issues.

Methodology

This review discusses the generation and detoxification of reactive oxygen species in the placenta and their roles in pregnancy complications.

Limitations

The review is based on existing literature and may not cover all aspects of oxidative stress in pregnancy.

Digital Object Identifier (DOI)

10.1016/j.bpobgyn.2010.10.016

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