The impact of carotid plaque presence and morphology on mortality outcome in cardiological patients
2006

Carotid Plaque and Mortality in Heart Patients

Sample size: 541 publication 10 minutes Evidence: high

Author Information

Author(s): Christina Petersen, Patricia B Peçanha, Lucia Venneri, Emilio Pasanisi, Lorenza Pratali, Eugenio Picano

Primary Institution: CNR, Institute of Clinical Physiology, Pisa, Italy

Hypothesis

Carotid plaque geometry and morphology can predict mortality in hospitalized cardiological patients.

Conclusion

Carotid plaque presence and morphology assessed by ultrasound are independent predictors of death in hospitalized cardiological patients.

Supporting Evidence

  • 83 all-cause deaths occurred during the follow-up period, representing 15% of the total population.
  • Patients with heterogeneous plaques had a higher risk of death compared to those with homogeneous plaques.
  • Age and the presence of heterogeneous plaque were identified as independent predictors of death.

Takeaway

Doctors can use ultrasound to look at the shape and type of plaque in the neck arteries to help predict if heart patients might die from their condition.

Methodology

The study involved 541 hospitalized patients who underwent ultrasound Duplex carotid scans and were followed for a median of 34 months.

Potential Biases

The visual assessment of plaque morphology is operator-dependent and may introduce variability.

Limitations

The study relied on subjective ultrasound assessments, which can vary between operators.

Participant Demographics

The average age of participants was 66 years, with 411 men and a variety of heart conditions.

Statistical Information

P-Value

0.000

Confidence Interval

95% CI 1.03–1.09

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-7120-4-16

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