Probiotic Properties of Lactobacillus plantarum Isolated from Ayurvedic Medicine
Author Information
Author(s): Kumar Himanshu, Rangrez Ashraf Y, Dayananda Kannayakanahalli M, Atre Ashwini N, Patole Milind S, Shouche Yogesh S
Primary Institution: National Centre for Cell Science, Pune, Maharashtra, India
Hypothesis
Can Lactobacillus plantarum isolated from Kutajarista reduce cellular damage caused by Aeromonas veronii?
Conclusion
Lactobacillus plantarum (VR1) from Kutajarista effectively reduces cellular damage caused by Aeromonas veronii in vitro.
Supporting Evidence
- VR1 showed tolerance to low pH and bile salts, indicating its potential as a probiotic.
- CFS of VR1 significantly reduced vacuole formation in Vero cells caused by A. veronii.
- Pre-incubation with VR1 CFS maintained tight junction integrity in MDCK cells exposed to A. veronii.
Takeaway
This study found that a type of good bacteria from an Ayurvedic medicine can help protect cells from damage caused by a harmful germ.
Methodology
The study involved isolating Lactobacillus plantarum from Kutajarista and testing its effects on Vero and MDCK cell lines exposed to Aeromonas veronii.
Limitations
The study was conducted in vitro, and further in vivo studies are needed to confirm the findings.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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