Miniature bioreactors: current practices and future opportunities
2006
Miniature Bioreactors: Current Practices and Future Opportunities
publication
Evidence: moderate
Author Information
Author(s): Jonathan I Betts, Frank Baganz
Primary Institution: University College London
Conclusion
Miniature bioreactors (MBRs) can significantly enhance the efficiency of bioprocess development by allowing high-throughput cell cultivation.
Supporting Evidence
- MBRs can perform many cell cultivations in parallel, speeding up bioprocess development.
- Different types of MBRs are based on existing bioreactor platforms like shaken devices and stirred-tank reactors.
- MBRs can reduce labor intensity and materials cost in bioprocess development.
Takeaway
Miniature bioreactors are small devices that help scientists grow many cells at once, making it faster and cheaper to develop new medicines.
Methodology
This review examines the use of miniature bioreactors in bioprocessing, discussing their applications, advantages, and limitations.
Limitations
Current miniature bioreactors may lack the instrumentation and sampling capabilities of larger systems, which can limit data quality.
Digital Object Identifier (DOI)
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