Outcome of Neonatal Hydronephrosis, a New Cut-Off to Identify Patients with Spontaneous Resolution
2024

New Cut-Off for Identifying Spontaneous Resolution in Neonatal Hydronephrosis

Sample size: 500 publication 10 minutes Evidence: high

Author Information

Author(s): Gatto Antonio, Ferretti Serena, Colonna Arianna Turriziani, Capossela Lavinia, Chiaretti Antonio, Covino Marcello, Rendeli Claudia, Ikezumi Yohei

Primary Institution: Fondazione Policlinico Universitario “A. Gemelli” IRCCS

Hypothesis

This study aims to identify APRPD cut-offs at birth to determine outcome stratification and second-level exams.

Conclusion

An APRPD value ≤ 8.5 mm can be used as a cut-off to reassure parents and clinicians of the benignity of postnatal dilatation.

Supporting Evidence

  • 279 patients (55.8%) had complete resolution at 6 months.
  • 344 patients (68.8%) had resolution at 9-12 months.
  • 353 patients (70.6%) had resolution at 24 months.
  • An APRPD value ≤ 8.5 mm showed a sensitivity of 80.4%.
  • An APRPD value ≤ 8.5 mm showed a specificity of 100.0%.
  • Children with prenatal UTD had a higher risk of persistent UTD.
  • 17.2% of children experienced at least one urinary tract infection.
  • 9.4% of newborns had an abnormal APGAR score (≤7) at birth.

Takeaway

Doctors found that if a baby's kidney dilation is less than 8.5 mm, it usually gets better on its own, so parents can feel more at ease.

Methodology

The study analyzed records of newborns with urinary tract dilation detected by ultrasound from 2010 to 2020, assessing their outcomes through follow-up examinations.

Limitations

Variability in follow-up length and interobserver variation in ultrasound measurements.

Participant Demographics

375 males (75.0%) and 125 females (25.0%), with 72.6% being term infants and 27.4% preterm.

Statistical Information

P-Value

0.000

Confidence Interval

95% CI [76.0–84.4]

Statistical Significance

p = 0.000

Digital Object Identifier (DOI)

10.3390/children11121437

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