基于分子网络技术识别新污染物及其转化产物的研究进展
2025

Advances in Molecular Networking Technology for Discovering Emerging Contaminants

publication Evidence: high

Author Information

Author(s): TAN Xiaomei, ZHANG Yuwei, JIAO Zhaoyu, YU Nanyang, WEI Si

Primary Institution: State Key Laboratory of Pollution Control & Resource Reuse, School of Environment, Nanjing University, Nanjing 210046, China

Hypothesis

How can molecular networking technology improve the identification of emerging contaminants and their transformation products?

Conclusion

Molecular networking technology enhances the identification and understanding of emerging contaminants and their transformation products in various environmental media.

Supporting Evidence

  • Emerging contaminants are widespread and pose unknown risks to health and the environment.
  • High-resolution mass spectrometry has advanced non-targeted analysis in environmental studies.
  • Molecular networking can cluster similar compounds and visualize complex datasets.
  • This technology has been successfully applied to identify new pollutants in various environmental media.
  • Studies show that transformation products can be more toxic than their parent compounds.

Takeaway

This study shows that scientists can use a special technique called molecular networking to find new types of pollution in the environment, which helps keep us safe.

Methodology

The study discusses the application of molecular networking based on high-resolution tandem mass spectrometry for non-targeted screening of emerging contaminants.

Limitations

The study acknowledges challenges in identifying compounds from complex data and the potential for false positives in network annotations.

Digital Object Identifier (DOI)

10.3724/SP.J.1123.2024.03014

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