The comparison of the efficacy of intramuscular tetracosactide and subacromial triamcinolone injection in rotator cuff tendinitis: a randomized trial
2024

Comparing Treatments for Rotator Cuff Tendinitis

Sample size: 86 publication 10 minutes Evidence: moderate

Author Information

Author(s): Orandi Amir Hossein, Mansour Amirpasha, Bagheri Nima, Majedi Hossein, Emami Meibodi Seyed Ali, Pestehei Seyed Khalil, Saberian Peyman

Primary Institution: Tehran University of Medical Sciences

Hypothesis

This research aimed to compare the effectiveness of intramuscular tetracosactide and subacromial triamcinolone injections in treating rotator cuff tendinitis.

Conclusion

Subacromial injection of triamcinolone is more effective than intramuscular injection of tetracosactide for pain relief and functional improvement in patients with rotator cuff tendinitis.

Supporting Evidence

  • Both treatment methods showed positive results during 4 weeks.
  • The triamcinolone group experienced a significant reduction in pain.
  • The tetracosactide group also showed improvement, but less than the triamcinolone group.

Takeaway

Doctors tested two types of injections to help shoulder pain. One type worked better than the other.

Methodology

86 patients with rotator cuff tendinitis were randomly assigned to receive either triamcinolone or tetracosactide injections, and their pain and functionality were assessed before and after treatment.

Potential Biases

Potential bias due to patients possibly using analgesics despite restrictions.

Limitations

The study did not assess the treatment's adverse effects and had a short follow-up period of 4 weeks.

Participant Demographics

Mean age of participants was 53.88 years, with 39.5% male and 52.32% having left shoulder involvement.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI 1.217–2.270

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/rap/rkae150

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