Evolution of GALA Proteins in Ralstonia solanacearum
Author Information
Author(s): Kajava Andrey V., Anisimova Maria, Peeters Nemo
Primary Institution: Centre de Recherches de Biochimie Macromoléculaire, CNRS, University of Montpellier 1 and 2, Montpellier, France
Hypothesis
Are GALA-LRR proteins members of the CC-LRR subfamily or a new subfamily?
Conclusion
GALA-LRRs belong to the CC-LRR subfamily and may have evolved through lateral gene transfer from plants.
Supporting Evidence
- GALA-LRRs have a specific consensus pattern that differs from known LRRs.
- Phylogenetic analysis suggests lateral gene transfer from plants.
- Positive selection was detected in certain GALA proteins.
Takeaway
This study looks at how certain proteins in bacteria might have come from plants and how they help the bacteria infect plants.
Methodology
Protein sequence analysis and structural prediction were used to classify GALA-LRRs.
Limitations
The phylogenetic analysis had low average branch supports, making it difficult to confidently suggest a putative donor.
Statistical Information
P-Value
<0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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