Screening of Tanzanian Medicinal Plants for Anti-Candida Activity
Author Information
Author(s): Runyoro Deborah KB, Matee Mecky IN, Ngassapa Olipa D, Joseph Cosam C, Mbwambo Zakaria H
Primary Institution: Muhimbili University College of Health Sciences
Hypothesis
The study aims to evaluate the anti-Candida activity of various plant extracts from Tanzanian medicinal plants.
Conclusion
The extracts that showed strong anti-Candida activity are worth further investigation to isolate and identify the active compounds.
Supporting Evidence
- Twenty-seven out of the 56 plants were found to be active against Candida albicans.
- Extracts of the root barks of Albizia anthelmintica and Balanites aegyptiaca showed strong activity.
- Almost 50% of the collected plants were found to be active against Candida albicans.
Takeaway
Researchers looked at 63 plants from Tanzania to see if they could help fight a fungus called Candida. About half of them worked well!
Methodology
Sixty-three plant extracts were evaluated for anti-Candida activity using the bioautography agar overlay method.
Limitations
The study did not identify the specific compounds responsible for the anti-Candida activity.
Participant Demographics
Plants were collected from four regions of Tanzania, including Coast, Dar es Salaam, Morogoro, and Tanga.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website