Near-Infrared Irradiation Induces Long-lasting Vasodilation
Author Information
Author(s): Tanaka Yohei MD, PhD, Matsuo Kiyoshi MD, PhD, Yuzuriha Shunsuke MD, PhD
Primary Institution: Shinshu University School of Medicine
Hypothesis
How does near-infrared irradiation affect long-lasting vasodilation in vascular smooth muscle cells?
Conclusion
Near-infrared irradiation nonthermally induces long-lasting vasodilation by causing apoptosis of vascular smooth muscle cells.
Supporting Evidence
- Near-infrared irradiation caused apoptosis of vascular smooth muscle cells.
- Significant increases in the cross-sectional areas of the lumen of the subdermal plexus were observed at postirradiation day 7 and day 30.
- No evidence of inflammation was found in irradiated samples.
- Apoptotic cells were detected at day 7 but not at later time points.
Takeaway
This study found that shining a special light on rats can make their blood vessels stay open longer by killing some of the muscle cells in the blood vessels.
Methodology
Rats were irradiated with near-infrared light, and their tissues were evaluated histologically at various time points.
Limitations
The study was conducted on rats, and results may not directly translate to humans.
Participant Demographics
Thirty male Wistar rats were used in the study.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
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