Suprafamilial relationships among Rodentia and the phylogenetic effect of removing fast-evolving nucleotides in mitochondrial, exon and intron fragments
2008

Phylogenetic Relationships Among Rodents

Sample size: 30 publication 10 minutes Evidence: moderate

Author Information

Author(s): Montgelard Claudine, Forty Ellen, Arnal Véronique, Matthee Conrad A

Primary Institution: Institut des Sciences de l'Evolution de Montpellier (UMR 5554), Université de Montpellier II

Hypothesis

What are the suprafamilial relationships among Rodentia and how does removing fast-evolving nucleotides affect phylogenetic analysis?

Conclusion

The study supports a fully resolved higher level rodent phylogeny with moderate to significant nodal support and identifies new inter-suprafamilial associations.

Supporting Evidence

  • The study used a large dataset of DNA sequences to analyze rodent relationships.
  • Fast-evolving positions were identified and removed to improve phylogenetic signal.
  • The results suggested new associations among rodent suborders.

Takeaway

Scientists studied the family tree of rodents using DNA and found new relationships between different groups of rodents by removing some fast-changing parts of their DNA.

Methodology

The study used ~7600 nucleotide characters from mitochondrial and nuclear DNA to analyze rodent phylogenetic relationships, removing fast-evolving positions to improve signal-to-noise ratio.

Potential Biases

Potential biases from fast-evolving sites affecting base composition and saturation.

Limitations

The removal of fast-evolving sites did not eliminate homoplasy completely and may have decreased resolution in some cases.

Participant Demographics

The study included 30 rodent species and 7 outgroup species.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2148-8-321

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