Association between the heart rate to temperature ratio and 28-day mortality in patients with heart failure in intensive care unit: a multicenter retrospective cohort study
2024

Heart Rate to Temperature Ratio and Mortality in Heart Failure Patients

Sample size: 3790 publication 10 minutes Evidence: high

Author Information

Author(s): Fu Cheng, Lin Weiguo, Chen Xinglin, Hong WeiLi, Yan Shaorong, Lin Yuzhan

Primary Institution: The Third Affiliated Hospital of Wenzhou Medical University

Hypothesis

This study aimed to investigate the relationship between the heart rate to temperature (HR/T) ratio and 28-day ICU mortality rates in patients with heart failure.

Conclusion

Higher HR/T ratios are associated with increased 28-day ICU mortality in patients with heart failure.

Supporting Evidence

  • The study found that the 28-day mortality rate increased significantly with a higher HR/T ratio.
  • Patients in the highest HR/T ratio quartile had a markedly elevated mortality risk compared to those in the lowest quartile.
  • The E-value analysis indicated that unmeasured confounders had a minimal impact on the results.

Takeaway

If a patient with heart failure has a higher heart rate compared to their temperature, they are more likely to have a serious outcome.

Methodology

This retrospective cohort study analyzed data from 3,790 patients with congestive heart failure using multivariable logistic regression.

Potential Biases

Potential unmeasured confounding factors could influence the results, although adjustments were made for several variables.

Limitations

The study only used the worst HR and temperature values within the first 24 hours of ICU admission, which may not reflect average values.

Participant Demographics

The study included 3,790 patients with heart failure, with a balanced distribution of gender and various ethnicities.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI: 1.17–2.04

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fmed.2024.1497245

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication