Nocturnal Hypoxia and Kidney Function Loss
Author Information
Author(s): Ahmed Sofia B., Ronksley Paul E., Hemmelgarn Brenda R., Tsai Willis H., Manns Braden J., Tonelli Marcello, Klarenbach Scott W., Chin Rick, Clement Fiona M., Hanly Patrick J.
Primary Institution: University of Calgary
Hypothesis
Does nocturnal hypoxia affect kidney function in patients with obstructive sleep apnea?
Conclusion
Nocturnal hypoxia is linked to an increased risk of accelerated loss of kidney function.
Supporting Evidence
- 44% of participants had nocturnal hypoxia.
- 5.7% of participants experienced accelerated loss of kidney function.
- Participants with nocturnal hypoxia had a nearly three-fold increased risk of accelerated kidney function loss.
Takeaway
If you have trouble breathing at night, it might hurt your kidneys over time.
Methodology
The study followed adults referred for sleep apnea testing, measuring kidney function over time and assessing nocturnal hypoxia.
Potential Biases
Participants were recruited from those referred for sleep apnea testing, which may introduce selection bias.
Limitations
The study may have residual confounding and potential referral bias, and it had a relatively short follow-up duration.
Participant Demographics
Participants were adults aged 18 and older, with a mean age of 55.2 years, and included a higher percentage of males (54.9%).
Statistical Information
P-Value
0.001
Confidence Interval
95% CI [1.25, 6.67]
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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