Magnesium Infusion and Pain Relief After Lung Surgery
Author Information
Author(s): Sampa Dutta Gupta, Koel Mitra, Maitreyee Roy, Suddhadeb Sarkar, Aniruddha Kundu, Sudeshna Goswami, Anupam Sarkar, Uday Narayan Sanki, Prakash Mitra, Ritabrata
Primary Institution: Institute of Postgraduate Medical Education and Research /SSKM Hospital, Kolkata, India
Hypothesis
Does intravenous magnesium infusion enhance the efficacy of thoracic epidural analgesia in patients undergoing lung volume reduction surgery?
Conclusion
Intravenous magnesium can prolong opioid-induced analgesia while minimizing nausea, pruritus, and somnolence.
Supporting Evidence
- Group A had a significantly longer duration of analgesia compared to Group B.
- Total doses of fentanyl and bupivacaine were significantly lower in Group A.
- Patients in Group A experienced significantly less pruritus, nausea, and vomiting.
Takeaway
Giving magnesium during surgery helps patients feel less pain and have fewer side effects from pain medicine.
Methodology
This was a single center, prospective, randomized, controlled, double-blind study comparing two groups of patients receiving different pain management regimens.
Limitations
Perioperative magnesium assay was not done, and target-controlled infusion for accurate dose delivery of opioids for the maintenance of analgesia was not available.
Participant Demographics
60 adult patients aged 35 to 60 years, ASA status II and III.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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