Eosinophilic Colitis: University of Minnesota Experience and Literature Review
Author Information
Author(s): Wolfgang B. Gaertner, Jennifer E. MacDonald, Mary R. Kwaan, Christopher Shepela, Robert Madoff, Jose Jessurun, Genevieve B. Melton
Primary Institution: University of Minnesota
Hypothesis
The pathophysiology of eosinophilic colitis is unclear but is suspected to be related to a hypersensitivity reaction.
Conclusion
Eosinophilic colitis is a rare condition that often responds well to dietary modifications in pediatric patients, while adult patients may require steroid treatment.
Supporting Evidence
- Five patients presented with diarrhea and hematochezia.
- Mean age at presentation was 26 years.
- Mean eosinophil count per patient was 31 per high-power field.
- Pediatric patients responded well to dietary modifications with no recurrences.
- Adult patients treated with steroids did not respond well.
Takeaway
Eosinophilic colitis is a rare disease that can cause stomach problems, especially in kids, and sometimes gets better with special diets.
Methodology
The study reviewed medical charts of patients diagnosed with eosinophilic colitis from 2003 to 2010, focusing on demographics, symptoms, diagnosis, and treatment outcomes.
Limitations
The study is based on a small sample size and lacks a control group.
Participant Demographics
3 pediatric patients and 2 adult patients, with a mean age of 26 years.
Digital Object Identifier (DOI)
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