Rapid and Reversible Recruitment of Early Visual Cortex for Touch
2008

Visual Cortex Recruitment for Touch

Sample size: 47 publication 10 minutes Evidence: moderate

Author Information

Author(s): Lotfi B. Merabet, Roy Hamilton, Gottfried Swisher, Jascha D. Kiriakopoulos, Elaine T. Pitskel, Naomi B. Kauffman, Thomas Pascual-Leone, Alvaro Pascual-Leone

Primary Institution: Beth Israel Deaconess Medical Center and Harvard Medical School

Hypothesis

Does sudden visual deprivation enhance tactile processing in the occipital cortex?

Conclusion

Five days of visual deprivation can lead to rapid and reversible changes in the occipital cortex, enhancing tactile processing.

Supporting Evidence

  • Blindfolded subjects showed improved performance on tactile tasks after five days of visual deprivation.
  • fMRI scans revealed increased activation in the occipital cortex in response to tactile stimulation after visual deprivation.
  • Repetitive transcranial magnetic stimulation (rTMS) disrupted Braille character recognition in blindfolded subjects but not in controls.

Takeaway

When people who can see are blindfolded for a few days, their brain starts using the part that usually sees to help them feel better.

Methodology

The study involved 47 normally sighted participants who were blindfolded for five days while undergoing tactile training, with assessments using fMRI and rTMS.

Potential Biases

Potential bias in participant selection and the effects of prior tactile training.

Limitations

The study's findings may not directly apply to individuals with progressive visual loss, as the conditions were different from those experienced by blind individuals.

Participant Demographics

47 normally sighted participants, aged 18-35, with 30 females.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0003046

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