The Chemistry of Gold Drugs
1994
The Chemistry of Gold Drugs
publication
Evidence: moderate
Author Information
Author(s): Peter J. Sadler, Rodney E. Sue
Primary Institution: Department of Chemistry, Birkbeck College, University of London
Conclusion
Gold compounds have potential therapeutic applications, particularly in treating rheumatoid arthritis and as antitumor agents.
Supporting Evidence
- Gold has been used in medicine since ancient times, with various applications documented.
- Gold(I) thiolate complexes have been shown to be effective in treating rheumatoid arthritis.
- Auranofin, a gold phosphine complex, is used for its anti-inflammatory properties.
- Gold compounds have shown potential cytotoxic effects against cancer cells in laboratory studies.
- Gold drugs may have side effects, including dermatitis and bone marrow suppression.
Takeaway
Gold has been used in medicine for a long time, and scientists are exploring new ways to use gold compounds to help treat diseases like arthritis and cancer.
Methodology
The study discusses various gold compounds, their properties, and their applications in medicine, particularly focusing on their use in treating rheumatoid arthritis and potential antitumor effects.
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