Cardiac magnetic resonance imaging in repaired tetralogy of Fallot: A longitudinal midterm follow-up study
2024

Cardiac MRI in Repaired Tetralogy of Fallot: A Follow-Up Study

Sample size: 56 publication 10 minutes Evidence: moderate

Author Information

Author(s): Houshmand Golnaz, Rahmati Rahem, Meftah Elahe, Zarimeidani Fatemeh, Khorgami Mohammadrafi, Ghorashi Seyyed Mojtaba, Fazeli Amir, Omidi Negar, Saedi Sedigheh, Motevalli Marzieh, Maleki Majid, Pouraliakbar Hamidreza

Primary Institution: Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

Hypothesis

This study aimed to highlight the parameters of cardiac magnetic resonance imaging (CMR) and their association with adverse outcomes in the midterm follow-up of patients with repaired tetralogy of Fallot.

Conclusion

Myocardial strain and ventriculoarterial coupling parameters could underscore personalized-approached therapy and follow-up to improve outcomes.

Supporting Evidence

  • 56 patients were assessed with a mean age of 15.23 years.
  • Right and left ventricular dysfunction occurred in 76.8% and 32.1% of patients, respectively.
  • Patients requiring pulmonary valve replacement had a significantly higher end-systolic volume index.

Takeaway

This study looked at heart scans of kids who had surgery for a heart problem called tetralogy of Fallot to see how their hearts were doing over time.

Methodology

This longitudinal study recruited patients with a history of tetralogy of Fallot total correction who had two CMR images at a minimum three-month interval.

Limitations

The sample may represent a subset of individuals with less advanced diseases, and the small number of outcomes limits the analysis.

Participant Demographics

Mean age of participants was 15.23 years with a 1:1 gender distribution.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0308362

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