Comparative review of three cost-effectiveness models for rotavirus vaccines in national immunization programs; a generic approach applied to various regions in the world
2011

Cost-Effectiveness Models for Rotavirus Vaccines

publication Evidence: moderate

Author Information

Author(s): Maarten J Postma, Mark Jit, Mark H Rozenbaum, Baudouin Standaert, Hong-Anh Tu, Raymond CW Hutubessy

Primary Institution: Unit of PharmacoEpidemiology & PharmacoEconomics (PE2), Department of Pharmacy, University of Groningen

Hypothesis

This study aims to critically review available cost-effectiveness models for rotavirus vaccination and compare their designs and outcomes.

Conclusion

The comparative approach is beneficial for low-income countries in designing their own cost-effectiveness analyses using existing models.

Supporting Evidence

  • Cost-effectiveness results of the models were quite similar despite differences in approaches.
  • Cost-effectiveness is highly sensitive to vaccine prices and mortality rates.
  • The study provides guidance for low- and middle-income countries on rotavirus vaccination models.

Takeaway

This study looks at different ways to measure how effective rotavirus vaccines are in saving money and lives, helping countries decide if they should use these vaccines.

Methodology

The study reviewed various cost-effectiveness models for rotavirus vaccination and compared their designs and outcomes using a standardized dataset.

Limitations

The results are based on a generalized dataset and may not reflect specific country conditions.

Digital Object Identifier (DOI)

10.1186/1741-7015-9-84

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