Glycopyrrolate in toxic exposure to ammonia gas
2011
Glycopyrrolate for Ammonia Gas Exposure
publication
Evidence: low
Author Information
Author(s): A Bhalla, S Mahi, N Sharma, S Singh
Primary Institution: Post Graduate Institute of Medical Education and Research, Chandigarh, India
Hypothesis
Can glycopyrrolate be an effective treatment for excessive secretions following ammonia gas exposure?
Conclusion
Glycopyrrolate can be a useful adjunct in managing excessive secretions in patients exposed to ammonia gas.
Supporting Evidence
- Glycopyrrolate reduced secretions significantly within minutes.
- The patient improved and achieved oxygen saturation of 95% after treatment.
- Indirect laryngoscopy revealed an edematous vocal cord.
- The patient was discharged after a 72-hour stay in the ICU.
Takeaway
If someone breathes in ammonia gas and has a lot of secretions, giving them glycopyrrolate can help them breathe better.
Methodology
Case report of a 45-year-old male treated with glycopyrrolate and supportive measures after ammonia exposure.
Limitations
Single case report limits generalizability.
Participant Demographics
45-year-old male, chronic smoker, with a history of COPD.
Digital Object Identifier (DOI)
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