Exploration of biological network centralities with CentiBiN
2006

CentiBiN: A Tool for Analyzing Biological Networks

publication Evidence: moderate

Author Information

Author(s): Junker Björn H, Koschützki Dirk, Schreiber Falk

Primary Institution: Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)

Hypothesis

CentiBiN will facilitate the analysis and visualization of centralities in biological networks.

Conclusion

CentiBiN helps systems biology researchers to identify crucial elements of biological networks.

Supporting Evidence

  • CentiBiN computes 17 different centralities for biological networks.
  • It supports various input formats and provides graphical representations.
  • CentiBiN is available as a free Java Web Start application and an installable Windows application.

Takeaway

CentiBiN is a computer program that helps scientists find the most important parts of biological networks, like proteins that interact with each other.

Methodology

CentiBiN computes and visualizes 17 different centralities for biological networks, supporting various input formats and graphical representations.

Limitations

Large networks with several thousand vertices are not displayed but can be analyzed and exported.

Digital Object Identifier (DOI)

10.1186/1471-2105-7-219

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication