Exercise and Brain Health: Understanding Neurotrophic and Cortisol Responses
Author Information
Author(s): Huynh Thinh, Rushing Baylie, Love Madeleine, Head Denise, Stojanovic Marta
Primary Institution: Washington University in St. Louis
Hypothesis
Does long-term exercise history and current physical activity levels predict neurotrophic and cortisol responses to acute exercise?
Conclusion
Current moderate-to-vigorous physical activity is important for neurotrophic responses and may reduce cortisol responses after exercise.
Supporting Evidence
- Higher current MVPA was associated with a greater neurotrophic response.
- Greater current MVPA was associated with a smaller cortisol response.
- Long-term physical activity did not influence neurotrophic or cortisol responses.
Takeaway
This study found that being active now helps your brain respond better to exercise, even if you haven't been active for a long time.
Methodology
Participants completed a questionnaire about exercise history, underwent a VO2 assessment, and wore actigraphy for seven days to estimate current physical activity.
Participant Demographics
Clinically normal middle-aged and older adults aged 43-85.
Statistical Information
P-Value
p=0.007 for neurotrophic response; p=0.044 for cortisol response.
Digital Object Identifier (DOI)
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