Olfaction and Cognitive Function in Older Adults
Author Information
Author(s): Yuan Yaqun, Chamberlin Keran, Li Chenxi, Luo Zhehui, Kucharska-Newton Anna, Shrestha Srishti, Simonsick Eleanor, Chen Honglei
Primary Institution: Michigan State University
Hypothesis
Poor olfaction is associated with a faster decline in cognitive function in non-demented older adults.
Conclusion
The study found that poor olfaction is linked to a quicker decline in cognitive function among older adults who do not have dementia.
Supporting Evidence
- Olfaction status was inversely associated with cognitive function test scores.
- Participants with moderate olfaction had lower cognitive scores compared to those with good olfaction.
- The decline in cognitive function was faster for those with poorer olfaction over 8 years.
Takeaway
If older people can't smell well, they might also have trouble thinking clearly as they get older.
Methodology
Participants completed the Brief Smell Identification Test and cognitive function was assessed using the Modified Mini-Mental State examination over multiple clinic visits.
Potential Biases
Potential bias due to death and loss to follow-up was accounted for in the analysis.
Participant Demographics
Participants were aged 71-82 years, 52.8% women, and 33.1% Black race.
Statistical Information
Confidence Interval
0.21-1.38 for moderate olfaction, 1.08-2.57 for hyposmia, 1.00-2.75 for anosmia.
Digital Object Identifier (DOI)
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