Is Bacterial Persistence a Social Trait?
Author Information
Author(s): Andy Gardner, Stuart A. West, Ashleigh S. Griffin
Primary Institution: St John's College, Oxford University; Institute of Evolutionary Biology, University of Edinburgh
Hypothesis
Persistence can be influenced by kin selection and may provide indirect benefits to other individuals in bacterial populations.
Conclusion
The study shows that bacterial persistence can be a social trait influenced by population structure and resource competition.
Supporting Evidence
- Persistence allows bacteria to survive during catastrophic events like antibiotic treatment.
- Reduced growth rates in persister cells can decrease competition for resources among bacteria.
- Relatedness among bacteria influences the level of persistence favored in populations.
Takeaway
Some bacteria can survive tough times by slowing down their growth, which can help not just themselves but also their friends in the same group.
Methodology
Theoretical modeling of bacterial populations to investigate the social consequences of persistence.
Limitations
The model assumes fixed parameters and does not account for varying environmental conditions or genetic turnover.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website