Novel therapies in breast cancer: what is new from ASCO 2008
2008

Novel Therapies in Breast Cancer from ASCO 2008

Sample size: 126 publication 10 minutes Evidence: moderate

Author Information

Author(s): David Chu, Janice Lu

Primary Institution: State University of New York at Stony Brook

Conclusion

Recent advances in targeted therapies have improved treatment options for metastatic breast cancer.

Supporting Evidence

  • Lapatinib showed a 40% overall response rate in HER2 positive relapsed/refractory inflammatory breast cancer.
  • Combination therapies involving bevacizumab and chemotherapy demonstrated improved progression-free survival.
  • New agents like HKI-272 and trastuzumab DM-1 are being investigated for their efficacy in advanced breast cancer.

Takeaway

Doctors are finding new ways to treat breast cancer that are less harmful and more effective than older methods.

Methodology

This review summarizes novel therapies presented at the ASCO 2008 meeting, focusing on targeted and biologic therapies for breast cancer.

Limitations

The review is based on presentations and may not include all data from ongoing studies.

Participant Demographics

The review discusses various studies involving patients with metastatic breast cancer, including those with HER2 positive and triple-negative breast cancer.

Digital Object Identifier (DOI)

10.1186/1756-8722-1-16

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