Epicardial Fat and Its Association with Cardiovascular Risk: A Cross-Sectional Observational Study
2010

Epicardial Fat and Cardiovascular Risk

Sample size: 97 publication Evidence: moderate

Author Information

Author(s): Mookadam Farouk, Goel Ramil, Alharthi Mohsen S., Jiamsripong Panupong, Cha Stephen

Primary Institution: Mayo Clinic

Hypothesis

Is there an association between echocardiographic epicardial fat and cardiac risk factors?

Conclusion

Epicardial fat greater than 5 mm is associated with cardiac abnormalities on echocardiography.

Supporting Evidence

  • EAT thickness >5 mm was associated with lower ejection fraction.
  • EAT thickness correlated with left ventricular mass.
  • Patients with higher EAT thickness showed trends towards hyperglycemia and hypertension.

Takeaway

This study found that having too much fat around the heart can lead to heart problems. It's easy to check with an ultrasound.

Methodology

A cross-sectional study using echocardiographic measurements of epicardial fat in 97 patients.

Limitations

The study did not find significant associations for some cardiovascular risk factors despite trends.

Participant Demographics

Mean age of participants was 66.44 years, with 60% being male.

Statistical Information

P-Value

<0.001 for age difference, 0.024 for ejection fraction, 0.01 for left ventricular mass index.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4103/1995-705X.76801

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