Spontaneous Occurrence of Gangrene Due to Clostridium septicum in a Patient With Advanced Endometrial Carcinoma
1994
Gangrene from Clostridium septicum in a Cancer Patient
Sample size: 1
publication
Evidence: low
Author Information
Author(s): David H. Moore, Kris Ghosh, Gregory P. Sutton
Primary Institution: Indiana University Medical Center
Hypothesis
Is there a link between Clostridium septicum gangrene and advanced endometrial carcinoma?
Conclusion
Clostridial gangrene should be considered in cancer patients with unexplained fever.
Supporting Evidence
- The patient had a history of recurrent endometrial adenocarcinoma.
- She presented with severe shoulder pain and discoloration.
- Gram stain revealed gram-positive spore-forming rods.
- She declined surgical intervention and died shortly after admission.
Takeaway
A woman with cancer got a serious infection called gangrene without any injury, and it happened really fast.
Methodology
Case report of a single patient with recurrent endometrial adenocarcinoma who developed spontaneous Clostridium septicum gangrene.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
63-year-old white female with recurrent endometrial adenocarcinoma.
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