Diet and Nutrition: Sunny Side of Cancer Prevention
2007

The Role of Vitamin D in Breast Cancer Prevention

Sample size: 972 publication Evidence: moderate

Author Information

Author(s): Mead M. Nathaniel, Julia Knight, Jacques Brisson, Reinhold Vieth

Primary Institution: Mount Sinai Hospital, Toronto

Hypothesis

Does vitamin D exposure during adolescence reduce breast cancer risk later in life?

Conclusion

Vitamin D-related exposures during adolescence may significantly reduce breast cancer risk.

Supporting Evidence

  • More frequent sun exposure during adolescence was associated with a 35% reduction in breast cancer risk.
  • Lower risk was linked to cod liver oil intake and drinking at least 10 glasses of milk per week.
  • A study found that women diagnosed in summer had a 15-25% better prognosis than those diagnosed in winter.
  • Observational studies suggest a 50% or more reduction in cancer risk with high vitamin D intake.

Takeaway

Getting enough sunshine and vitamin D when you're young can help lower the chances of getting breast cancer when you're older.

Methodology

Case-control study involving interviews about vitamin D-related exposures among women with breast cancer and healthy controls.

Potential Biases

Potential recall bias in self-reported sun exposure and dietary habits.

Limitations

The study may not account for all factors influencing breast cancer risk.

Participant Demographics

972 women with newly diagnosed invasive breast cancer and 1,135 healthy controls.

Statistical Information

Statistical Significance

p<0.05

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